The Definitive Guide to sayaph
The Definitive Guide to sayaph
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Pelajar SMP tawarkan layanan seks, 'terindikasi korban eksploitasi seksual' dan 'titik kritis' pendidikan seks anak
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The distance between the oxygen atom of Thr164 of Aph1 as well as the oxygen atom of Tyr466 of PS1 is predicted being 3.5 Å, suggesting that a hydrogen bond (H...O distance, approximately 1.8 Å) is formed in these aspect chains (determine 7b). The T164A mutation might remove the hydrogen bond with PS1 Y466, resulting in versatile movement of the carboxy terminus of PS1. We suggest that Aph1 mutations regulate protease activity by means of conformational improvements in PS1.
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